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Clinical presentations and outcome of severe community-acquired pneumonia

Identifieur interne : 002B93 ( Ncbi/Merge ); précédent : 002B92; suivant : 002B94

Clinical presentations and outcome of severe community-acquired pneumonia

Auteurs : Mousa Elshamly [Égypte] ; Mohamed O. Nour [Égypte] ; Abdelmaaboud M. M. Omar [Égypte]

Source :

RBID : PMC:7125902

Abstract

Background

Severe community-acquired pneumonia (SCAP) represents a frequent and potentially life-threatening condition. About 10% of all hospitalized patients with CAP require admission to the intensive care unit (ICU), and the mortality of these patients reaches 20–50%.

Objective

To evaluate the clinical presentation, bacteriological profile and outcome of severe community-acquired pneumonia (SCAP).

Patients and methods

54 patients presented by symptoms and sign of severe community acquired pneumonia who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital from August 2015 to March 2016 were subjected to full clinical examination, chest X ray, complete blood picture, sputum and blood culture, PCR for suspected cases of Influenza H1N1 and MERS-COV, treatment, follow up, data collections and statistical analysis.

Results

The present study included 54 patients 26 males and 28 females with SCAP who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital. The most common comorbidities were diabetes mellitus and hypertension. The most common presentations were fever, cough, dyspnea and hypoxemia. Two patients developed renal failure and 4 patients developed septic shock. The most common isolated organism was Streptococcus pneumoniae, Influenza H1N1, and Staphylococcus aureus. Mortality was 24% and it was common in patients with comorbidity than in patients without comorbidities.

Conclusion

SCAP occurs more frequently in those with comorbidities. The most frequent isolated causative organism of SCAP is S. pneumoniae, Influenza H1N1 and S. aureus. SCAP is associated with significant mortality, early recognition and prompt treatment may improve outcome.


Url:
DOI: 10.1016/j.ejcdt.2016.06.002
PubMed: NONE
PubMed Central: 7125902

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PMC:7125902

Le document en format XML

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<title>Background</title>
<p>Severe community-acquired pneumonia (SCAP) represents a frequent and potentially life-threatening condition. About 10% of all hospitalized patients with CAP require admission to the intensive care unit (ICU), and the mortality of these patients reaches 20–50%.</p>
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<sec>
<title>Objective</title>
<p>To evaluate the clinical presentation, bacteriological profile and outcome of severe community-acquired pneumonia (SCAP).</p>
</sec>
<sec>
<title>Patients and methods</title>
<p>54 patients presented by symptoms and sign of severe community acquired pneumonia who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital from August 2015 to March 2016 were subjected to full clinical examination, chest X ray, complete blood picture, sputum and blood culture, PCR for suspected cases of Influenza H1N1 and MERS-COV, treatment, follow up, data collections and statistical analysis.</p>
</sec>
<sec>
<title>Results</title>
<p>The present study included 54 patients 26 males and 28 females with SCAP who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital. The most common comorbidities were diabetes mellitus and hypertension. The most common presentations were fever, cough, dyspnea and hypoxemia. Two patients developed renal failure and 4 patients developed septic shock. The most common isolated organism was
<italic>Streptococcus pneumoniae</italic>
, Influenza H1N1, and
<italic>Staphylococcus aureus</italic>
. Mortality was 24% and it was common in patients with comorbidity than in patients without comorbidities.</p>
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<p>SCAP occurs more frequently in those with comorbidities. The most frequent isolated causative organism of SCAP is
<italic>S. pneumoniae</italic>
, Influenza H1N1 and
<italic>S. aureus</italic>
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<name sortKey="Yezli, S" uniqKey="Yezli S">S. Yezli</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="research-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Egypt J Chest Dis Tuberc</journal-id>
<journal-id journal-id-type="iso-abbrev">Egypt J Chest Dis Tuberc</journal-id>
<journal-title-group>
<journal-title>The Egyptian Journal of Chest Diseases and Tuberculosis</journal-title>
</journal-title-group>
<issn pub-type="ppub">0422-7638</issn>
<issn pub-type="epub">2090-9950</issn>
<publisher>
<publisher-name>The Egyptian Society of Chest Diseases and Tuberculosis. Production and hosting by Elsevier B.V.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmc">7125902</article-id>
<article-id pub-id-type="publisher-id">S0422-7638(16)30036-X</article-id>
<article-id pub-id-type="doi">10.1016/j.ejcdt.2016.06.002</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Clinical presentations and outcome of severe community-acquired pneumonia</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" id="au005">
<name>
<surname>Elshamly</surname>
<given-names>Mousa</given-names>
</name>
<email>dr-mousa_elshamly@hotmail.com</email>
<xref rid="af005" ref-type="aff">a</xref>
<xref rid="cor1" ref-type="corresp"></xref>
</contrib>
<contrib contrib-type="author" id="au010">
<name>
<surname>Nour</surname>
<given-names>Mohamed O.</given-names>
</name>
<email>drmun78@yahoo.com</email>
<xref rid="af010" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author" id="au015">
<name>
<surname>Omar</surname>
<given-names>Abdelmaaboud M.M.</given-names>
</name>
<email>abdelmaaboudm@yahoo.com</email>
<xref rid="af015" ref-type="aff">c</xref>
</contrib>
</contrib-group>
<aff id="af005">
<label>a</label>
Department of Chest Diseases, Faculty of Medicine, Al-Azhar University, Egypt</aff>
<aff id="af010">
<label>b</label>
Department of Community & Occupational Medicine, Faculty of Medicine, Al-Azhar University (Damietta Branch), Egypt</aff>
<aff id="af015">
<label>c</label>
Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Egypt</aff>
<author-notes>
<corresp id="cor1">
<label></label>
Corresponding author.
<email>dr-mousa_elshamly@hotmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="pmc-release">
<day>18</day>
<month>6</month>
<year>2016</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub">
<month>10</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>18</day>
<month>6</month>
<year>2016</year>
</pub-date>
<volume>65</volume>
<issue>4</issue>
<fpage>831</fpage>
<lpage>839</lpage>
<history>
<date date-type="received">
<day>17</day>
<month>3</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>2</day>
<month>6</month>
<year>2016</year>
</date>
</history>
<permissions>
<copyright-statement>© 2016 The Egyptian Society of Chest Diseases and Tuberculosis. Production and hosting by Elsevier B.V.</copyright-statement>
<copyright-year>2016</copyright-year>
<copyright-holder>The Egyptian Society of Chest Diseases and Tuberculosis</copyright-holder>
<license>
<license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
<abstract id="ab005">
<sec>
<title>Background</title>
<p>Severe community-acquired pneumonia (SCAP) represents a frequent and potentially life-threatening condition. About 10% of all hospitalized patients with CAP require admission to the intensive care unit (ICU), and the mortality of these patients reaches 20–50%.</p>
</sec>
<sec>
<title>Objective</title>
<p>To evaluate the clinical presentation, bacteriological profile and outcome of severe community-acquired pneumonia (SCAP).</p>
</sec>
<sec>
<title>Patients and methods</title>
<p>54 patients presented by symptoms and sign of severe community acquired pneumonia who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital from August 2015 to March 2016 were subjected to full clinical examination, chest X ray, complete blood picture, sputum and blood culture, PCR for suspected cases of Influenza H1N1 and MERS-COV, treatment, follow up, data collections and statistical analysis.</p>
</sec>
<sec>
<title>Results</title>
<p>The present study included 54 patients 26 males and 28 females with SCAP who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital. The most common comorbidities were diabetes mellitus and hypertension. The most common presentations were fever, cough, dyspnea and hypoxemia. Two patients developed renal failure and 4 patients developed septic shock. The most common isolated organism was
<italic>Streptococcus pneumoniae</italic>
, Influenza H1N1, and
<italic>Staphylococcus aureus</italic>
. Mortality was 24% and it was common in patients with comorbidity than in patients without comorbidities.</p>
</sec>
<sec>
<title>Conclusion</title>
<p>SCAP occurs more frequently in those with comorbidities. The most frequent isolated causative organism of SCAP is
<italic>S. pneumoniae</italic>
, Influenza H1N1 and
<italic>S. aureus</italic>
. SCAP is associated with significant mortality, early recognition and prompt treatment may improve outcome.</p>
</sec>
</abstract>
<kwd-group id="kg005">
<title>Keywords</title>
<kwd>Presentation</kwd>
<kwd>Outcome</kwd>
<kwd>Severe community acquired pneumonia</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
<affiliations>
<list>
<country>
<li>Égypte</li>
</country>
</list>
<tree>
<country name="Égypte">
<noRegion>
<name sortKey="Elshamly, Mousa" sort="Elshamly, Mousa" uniqKey="Elshamly M" first="Mousa" last="Elshamly">Mousa Elshamly</name>
</noRegion>
<name sortKey="Nour, Mohamed O" sort="Nour, Mohamed O" uniqKey="Nour M" first="Mohamed O." last="Nour">Mohamed O. Nour</name>
<name sortKey="Omar, Abdelmaaboud M M" sort="Omar, Abdelmaaboud M M" uniqKey="Omar A" first="Abdelmaaboud M. M." last="Omar">Abdelmaaboud M. M. Omar</name>
</country>
</tree>
</affiliations>
</record>

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